The executive branch of the Cherokee Nation is charged with executing the laws of the Cherokee Nation, establishing tribal policy and delegating authority as necessary for day-to-day operations of all programs and enterprises administered by the Cherokee Nation tribal government. These leaders include the Principal Chief, Deputy Principal Chief and seven cabinet positions appointed by the Principal Chief and confirmed by the Tribal Council. The seven cabinet-level positions within the executive branch include, Secretary of State, Chief of Staff, Treasurer, Marshal, Attorney General, Secretary of Natural Resources and Secretary of Veterans Affairs. 

The Principal Chief and Deputy Principal Chief are elected by the popular vote of Cherokee Nation citizens and may serve up to two consecutive four-year terms.